What do you mean 'Not possible'?
the anatomy of animals and humans are both very different
the biological make up of humans does not directly transfer over to animals
aka
anthropomorphic animals should not be muscular men that have stripes and stuff with some carpeting on their entire body and a tony the tiger nose
it's an animal
it's still an animal
it just has humanly characteristics such as talking or walking on two legs (both of which aren't anatomically possible in most, but even still)