I assume he's referring to HRT since there are no girls on the internet (especially not on lego forums)
I forget what movie it was but there was a specific part where this really fine girl looks over at this "presumably" transgender girl (or a girl who feels she's in the wrong body) and she says:
"Honey, your brain doesn't make you a woman, these make you a woman" (shakes her chest)
I was like damn... she makes a really good point though....