NES: Snake Rattle and Roll/Base Wars
SNES: Chrono Trigger/aerobiz
Sega Genesis: Mutant League Hockey/ Sonic 2
N64: Goldeneye
Dreamcast: Phantasy Star
Playstation: Grandia/FF8/Lunar2/chrono Cross
Playstation 2: Twisted Metal: Black/Futurama
Xbox: Star Wars: Knights of the Old Republic
Xbox 360: Fable II, Fallout III, Mass Effect, Star Trek Legacy
This is just my opinion based from game systems I've owned or played on.