Would 1) Cause the earth to move, thrown off axis, or even badly damage it and 2) wouldn't be a powerful enough missile to blow it into that small peices without mangling the planet.
Holy forget... What kind of weapon has that sort of yield? >:O
I know you guys all think that nuclear weapons can blow up entire continents but they are nowhere near that powerful. The first 2 atomic bombs used in combat only destroyed about 25 square miles of a city. Sure..fallout and such damaged more, but it is not like half of Japan was a crater.
Believe me, there is no weapon on earth, yet, that could seriously alter the orbit of the moon or the earth itself.