This game is freekin awesome.
Do all the side-quests you can and max out your small guns and repair skills. :D
I have small guns at 90 and repair at 100, but I wear Vance's longcoat so theres no need to get it to 100.
Also 100 lockpick and almost 100 sneak and melee weapons.
you know, if you put all your special points into intelligence when you start and then run to rivet city and get the bobble head of intelligence, you get stuffloads of points when you level. And with the comprehension perk and the use of books and maybe clothing, you can get all skills to 100. That combined with the "Almost special perk" would probably make the game just too easy.