I bet Randy becomes one and Cartman is a hater, Kyle is neutral, Kenny will die, and Stan will be pulled into it somehow.
All i know is that this episode will spawn stuff just like how it spawned jew jokes.
No matter how it turns out, the parts of the internet with at least a small brony population are going to be a huge ass battlefield.
Also we are going to get mertic craptonnes of people that act as if they are genuine bronies because of south park, no matter if the episode has a positive or negative impact.
Just expect a stuffstorm. A very large one.
It'll start silently as it is now, and as time progresses the entire internet will become a 3 sided-battlefield of haters, bronies and die-hard southpark fans.