Ah, this is one of my favorite movies (the 80s one).
I have always liked the concept of the movie. Almost every scary movie nowadays relies on jump scares or just super creepy things. This movie was scary because you didn't know who was 'the thing' and who was human. You never knew what would happen next because you never knew who 'the thing' was.
Hopefully you can capture this same feeling, a feeling of paranoia, from the gameplay and build. I love games where I am nervous almost the entire time.
Also, I'd love to help with this. I have always wanted to make something based on this movie. I am up for helping with the build or maybe even administrating when it's hosted.