I came across this page on a pretty cheesy site entitled "12 Zodiac Signs Reborn as Horrifying Monsters", and immediately realized how epic a game could be if it was based around these monsters. I was thinking like a Dark Souls/Shadow of The Colossus type game.
If someone made a game where you had to defeat these 12 monsters, I would immediately buy it.
Here's the
siteHere's some of the cool ones -
AeriesGeminiTaurus