All the words there can be considered insensitive, though it depends on how you use them.
There's always a set of general insults that are ok to say when justified, or if it isn't directed at a person, like cunt or stuffhead.
Then there's the more specialized terms that will always offend a group/idea, like monday and bible humper (and maybe friend).
And then there's stuff like "downy" or handicap if directed at someone actually handicapped that are tasteless.
If variety 2 or 3 apply/offend you, then fine, speak up.
If variety 1 offends you, either get thicker skin or just cover your ears.
Basically that ^
I think friend would be offensive, since it's a derogatory term for a homoloveual male and the world had gotten a lot less homophobic lately (that or people are just hiding it better)