I'm going to be clear here and be the guy who points this out, people who are having issues are either doing the following :
Outdated Drivers (#1 Culprit of stuffty performance and buggy devices)
Outdated Programs (#1 Culprit of programs not responding or working properly)
stuffty Antivirus giving 99% disk usage (very common, ditch what you have and use just use bitdefender free, or full)
30 Items running at startup (Check task manager and go to the startup tab, probably a large amount of stuff running)
Virus,Malware,Spyware (Windows 10 is a pretty tough nut to crack, but if your stupid enough you can still get these)
DIY Registry tweaks (Yeah we all like to mod Windows a bit, but sometimes these can break and give you a bad time)
Uxstyle Theme Patch(It will break and it will cause you pain, best to un-patch before the upgrade)
Browser Extension thats a virus (These are starting to be common if you use a chromium based browser or a firefox based one)
You most likely have one of these but in the rare case you don't do the following as a last resort:
Get yourself a huge USB drive, save all your important stuff onto it, the do a clean install of windows 10 by using the Windows 10 media creation tool (Get it from the ISO page of Windows 10) make sure you choose to not keep anything.
Now if after you still deal with this stuff its either the thing you saved in the flashdrive is causing the issue or your better off waiting for Windows 10 to be compatible with watever the hell your using.