Welcome. (I searched and I hope this wasn't taken.) You have two options:
#1: What would you do to...
OR
#2: What would you do with...
Now, the instructions to playing:
One Person: What would you do to Global Warming?
Replier: Burn the world.
What would you do to Cake?
So it basically goes on and on. So I'll start.
What would you do with Cake?