Little things that really piss you off?

[Peejster]

For me, that'd be people spelling my name "Peejester"

[Ad Bot]

[Nymethus]

People that look into whatever they're taking the photo with when they take a photo of themselves.

[Masterlegodude]

Cave Story
Halo 2 and Halo 3
Certain songs in Rock Band games

Yes i have anger issues

[Barakuda]

People who spell my last name wrong and people who have no manires while eating.

[Masterlegodude]

people who have no manires while eating.

I think you mean "manners"

[LaCuckooRacha]

People who spell "Should've" "Should of".
People who don't use question marks when asking a question.
People who don't use the spell checker.

Yes, I'm a grammar national socialist.

[Masterlegodude]

People who spell "Should've" "Should of".

"Should've" is "should" and "have" mixed together, why do people think it's "should" and  "of" mixed together?

[Madmitten]

When everyone cannot spell my loving name right(in RL)

[Nymethus]

People who have no marines while eating.

[WhoDa?]

politician and religious people.

[Platinum]

People who write/type "your" instead of "you're" when the mean "you are".
People who spell my last name with a K instead of a C.
...And religious people.

[Tokthree]

When I can't find Waldo 

[LaCuckooRacha]

Pure carbon atoms.  I just can't stand them.

[oromis]

Leetle scout piss heavy weapons guy off

[snot2]

using then instead of than