Anyone that plays video games has reflexive movements. When you want to shoot, you don't think "Okay, now I need to press the mouse button.", you just do it.
My father doesn't do that though. It's almost embarassing watching him play a shoot 'em up.
In the middle of combat he has to stop and look down at his controller to find the right buttons. :s
Might have something to do with him being dyslexic and or other things going on in his brain.
Yet, he's oddly good at playing with the Wii, even on new games where he doesn't know how to move the controller in the way the game wants.