IE is awkward and annoying, very interruptive with its naggy messages and general ugliness.
Google Chrome can be a tad frustrating on startup, but once you get used to the interface is very good.
Firefox used to be king of all browsers, but a few versions a go it turned into a gigantic piece of IE-grade stuff.
Safari is adequate, a good choice for a clean streamlined browser but a bit of an initial bitch with its Flash-naggery.
Opera is nice but it seems to self-deteriorate when you have it installed for a long time and turns ugly, even if you clean the cache something laggy sticks around.