Reboot would be the basic thing to do. It works as magic man. =) you can pres ctrl alt del and theres an option there taht saya restart.
What Windows version are you using?
Try Win+ArrowThatIsn'tDown.
Windows XP home editionIf it helps, I installed a new gpu and ram a while ago but the drivers and whatnot are already installed.I also got a new mouse.