if you don't need that much harddrive space, I'd say ditch the 500 and 250GB HDD's and get yourself an SSD. use the 1TB for your games and files and stuff, and use the SSD for windows and the like. nobody likes waiting for their OS to boot or important programs to open.
alternatively (since from your last post it seems like you do need the space) you could ditch the 500 and the 250 for another 1TB HDD. see bisjac's post for reasoning to this.
however a good rule with SSD's is this: if you're not sure if you need one, you don't need one. however since you said you have money to burn, why not?
as has been suggested, I also recommend a GPU upgrade. however I need an entire revamp myself so I wouldn't be the guy to ask on what model to buy, maybe Ethan will come into the thread since he seems to know quite a bit about building computers and what parts to choose.
also since your keyboard was "stuffted up" or however you put it, consider investing $100 or so into a nice keyboard with more features than a basic one.
