I used to sleep in pyjamas, then I started sleeping in just my underpants and now I sleep naked and I have found no reason to go back to sleeping in any item of clothing. I'm not prone to nighttime emissions, I don't believe that sleeping in clothing is any more or less hygienic than sleeping naked and I have no fear of anyone coming into my room while I'm asleep and, even if they do, it's on them since I'm an adult man and nobody should have any reason to come into my room while I'm asleep.
It probably helps that I have hypersensitivity and some pretty loving amazing blankets that feel fantastic against my skin, I can definitely see these two factors alone making it worth it for me.