What like just my neighborhood? If it just took out my neighborhood I wouldn't really give a forget and I'd just try and take all the most expensive to replace stuff like my PC.
Or a full on nuclear weapon? I live in Australia, so I'd essentially be forgeted. Basically everything you could use to prep for a disaster is probably banned. I own a canteen and a military combat uniform (boots included) so I guess I'd take those, along with a backpack and my bike helmet, plus my leather jacket and raincoat I guess for some level of environmental protection. I'd grab the duct tape and probably one of the large extension cables downstairs to use as improvised rope since I currently don't own any. I'd try and take my mountain bike too. Probably try and grab all the tools I could out of the garage, including the big flashlight (and a forgetload of batteries). Also, a ton of underwear and socks, kek. I've got a lighter somewhere in my room, which would be handy.
I guess I'd take the biggest knife I could find in the kitchen as an improvised weapon but I wouldn't expect it to last very long. Either way that's basically everything I have at my disposal in this house lol