The thing is, everyone likes their controls. The whole point of custom controls is that you can set them to whatever you want. In Blockland, I use the arrow keys for movement. Everyone elses uses ASWD. I use in ASWD in every other game. The reason is, in Blockland, I don't have to reach across the keyboard to press R to reload, F1 to swap, B to drop a bomb, etc... I use the arrow keys because they are close to the building keys.
Now if you are playing an FPS, one good idea is to set swapping secondary weapons to backward scroll wheel, swap primaries to scrolling forward, pressing the scroll wheel reloads, and the 4th mouse button does some other combat related command. But that isn't Blockland, is it?
I'm in the mood for really long posts today. Well, longer than average at least.