Samus at the end of Metroid Prime 3 with the Hazard Shield, the Nova Beam and a Hyper Mode that allows her to generate Phazon into her arm cannon and an X-ray Visor that detects a weak body part inside of the enemy...
Ouch.
Doesn't matter.



Immunity to AOE for 10 seconds, immunity to Range for 10 seconds, and immunity to everything for 10 seconds in which I can heal myself.
To be fair, samus would probably beat up on the other 3 classes, especially robotics and recon.
Also while we're already comparing 2 fictional universes, lets compare the Federation from Star Trek to the Empire from Star Wars. I say the Empire because they have fighters, and lots of them.