Maybe
If both graphic cards are Nvidia/Ati the same mark you shouldnt' but for precaution only it's recommended to remove your drivers first then insert the new graphics card, then reinstall the correct/same drivers again.
I saw that ninja.
wtf
And you also do the bus.(Thats your Que.)
only one person here gave me some help,the rest of you....
I helped you. I said no.