Depression is a very intensifying state of mind which most've us can, or will feel. It is completely normal for the certain lack of motivation, or negative inlook you have, but take note that some of the things that you're looking into, may only seem irrational and somewhat absurd, because you may be expecting these certain things to be as inconvenient as they seem to you.
Take not that they're most likely not, and may be of a least extent than what you expect. It is difficult to try and look positive through so much inconsideration and low motivation; but these certain things do not make you "a nobody" or "a speck," they do not determine whether you are useful or not, because you are useful as being an individual.
You do not need to expect people to tell you who to be, if you want to make your own diverse opinions, or live your own life in your own perspective. Certain things like what you are talking about will become an obstacle in your life, and may seem like they are constant and merely irresolvable, but take note that rationalizing on these certain things, and treating them as if they are not as severe as you think, will help you resolve them, or have a better, and much more positive idea to what they seem to you.
People not putting as much empathy or focus towards you, may be the case, but I highly doubt that will be everyone's input towards you. Try and focus on being yourself near your friends, and if they seem to be ignoring you obnoxiously, maybe you should try and spend time with them more often, or see if it may be something that is bothering them. It certainly would not hurt to get a little perspective on these reasons why, than to just let them sit there.
It would help if you did read through this, regardless of how long it is. I can't really summarize because I'm on a bunch of topics.