I'm playing on Medium. I wait until the last moment to use medkits, but as I said before, I don't use plasmids much.
Do you have any explosives/armor-piercing rounds?
I use Plasmids almost constantly :S
I do have armor-piercing rounds, but very few so they don't really do much damage. No explosives yet. I just got to the part where that martyr fisherman guy stops me from getting to Lamb.
Has anyone else picked up on the fact that Delta must be related to Ryan? He can use the Vita-Chambers, and it was stated in BioShock 1 that they were only desinged for Ryan, but they were faulty and would let anyone related to him use them. Sorry if I hinted anything that spoils BioShock 1 for anyone who hasn't beaten it yet, try not to think about it too hard and hopefully it won't spoil a thing.