Several:
Dev From Heatseeker - Such A Motherloving Chatterbox, Always Saying "Gotta Take Down Those Fights, DT"
The Spotted Elephant Things Jumping In Front Of the House On Super Mario Galaxy When You Save Luigi From The Top Of The House - They're Just Annoying
Toadsworth - My God, Such An Uppity Little Bitch
Captain Falcon - Must I Say Why?
The Guys With The Hazmat Suits On In The Midway On Crash Tag Team Racing - Ok, No Radiation Leak, Why You Wearing Those Things? And they're Also: Fat, Stupid, And They Don't Know How To Defend themselves