Don't forget the fact that the entire world kinda depended on the United States existing so the internet wouldn't fall apart (its kind of important) and the world's economies wouldn't stuff themselves.
Oh, and the fact that the ESTO did this because they felt the United States was being too big of a world policemen.
The Midwest and the South probably has isolationist/self-dependency policies in place as well; note: the Midwest is socialist, the South is fascist, and the Union hardly exists.
They won't trade with you, including the companies.