Alchemy is great if you want to use potions and stuff, but quite honestly it's not worth much effort.
If you can poison a stuffload of 250 or so arrows, and get a bundle of Healing Potions working then you're in pretty good shape. Yet still, not completely worth it unless you want to be constantly pressing that bound key.
Also, the fact that the monsters get periodically harder and more frequent to match your level kind of pisses me off. I expected to get that whole "Hi, I'm Jesus Christ! *Strikes down Daedric Lord*" when I hit level 72. Not exactly...
Instead I get uber-ass motherforgeters the size of Godzilla to fight in the Meadows. In the Meadows.
Frolicking through the flowers comes with a price now, not just a couple of deer and wolves.
But gigantic loving trolls instead. It's great.
Also, if anyone could help me out with the "Hugantic Heist" quest for the Thieves guild, apparently the Blind Monks that are supposed to give me the scrolls can see perfectly fine. At least well enough to throw hundreds of critical hits on me with a Katana? Wut.