Thank you, Sheezy.
And @robonoob
Long term affects? Varies, depending on what other source you want to blame symptoms on. If you choose to ignore the fact that it's often addictive, I'd say the anxiety/nervousness. Anxious thoughts can take root in your brain if you're affected by it too much, no matter how irrational they can be.
"UR LUNGS" do indeed get forgeted, inhaling anything other then then standard mix of oxygen and nitrogen. I don't see why you want to keep this out of the argument.