I learned how to throw pocket knives about 2 years ago and I have 7 heavy weighted 6" folding knives, 1 ninja star and one self made hand-crossbow. I miss fired it once and ripped off all the skin on the top of my index finger, with enough remaining force to poke a 2" hole in the wall.
But I'd probably just call 911 and hide with my knives so I could give the cops inside info. Unless I hear gunshots, there's no need to go full aggro, cause that's how YOU die.
Given that I've lived in my house for a while now, I know all the spots that creak and all the spots that allow you to be dead silent, not to mention the spots in my house that allow you to hide perfectly unseen. I also have a personal bathroom, so I could hide in the mini hall leading to my bathroom, wait for the door to open and the floor board beneath my door to creak, then make a wide swing from around the corner with any one of my knives.
As a member of NHAA, one of the biggest recommendations they make for home defense is a surprise counter attack.