Going into the Glowing Sea for the first time on this character, as part of the main storyline.
Quick travel to closest location, on the other side of the river.
Am wearing power armour for the mission, upgraded as much as my abilities allow, for radiation resistance, and to survive Deathclaws and Scorpions.
Wander down the road to the nearest bridge (which was an open drawbridge, so couldn't cross it anyway), as I don't have Aquagirl ability.
Approach a building with super mutants, while on the road. They attack.
Hanrooster gets forgeted over instantly, Super Mutants are giving me a beating.
Wander backwards, as Hounds, Skirmishers and a Self Deleter chase me.
Nearly have the Self Deleter down, when I have to reload. He explodes.
Left leg destroyed, and left arm damaged.
Finish off the other super mutants on the ground.
One still left on top of building with laser rifle.
Shoots wildly at me, while I line up some sniper shots.
Car next to me catches fire, from his shots, and then explodes almost instantly.
Lose second leg.
Restart to before quick travel.
My most humiliating non-fatal defeat yet.
What? That's not true. I've killed all three of them. Only the children are essential.
The wiki says they are essential.
And I'm certain at the very least I couldn't kill Ingram when forced to.
Maybe it has to do with your point in the storyline? I hadn't finished at the time.