As long as we're on the subject of musical instrument control schemes...
The plan I had for that aformentioned NES-style project was that using the lute item would disable your usual controls and effectively turn your computer keyboard into a simplified naturals-only musical keyboard. Z, X, C, V, B, N, and M would play the lower octave while A, S, D, F, G, H, J, K, L play the upper octave.