sometimes, not always
I was jungling and started to lag horribly, so I couldn't see where people were and everything was drifting (health bars were the only thing working lol), but I could still give input and hope it worked
I was sitting at wraiths, saw people drifting together at mid, and just started telling my guy to attack people and spin places
it was intense, it was probably like 4 enemies there that I initiated on, and somehow got 2 kills, ulted as I was about to die, and walked out, letting my team clean up
so yes, it takes a fair amount of right clicking, but it doesn't have to be precise at all
(I really wish I could've recorded that fight though)